Chih-Hao Lee Selected Research

PPAR delta

6/2008	Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity.
3/2008	PPARdelta-mediated antiinflammatory mechanisms inhibit angiotensin II-accelerated atherosclerosis.
3/2008	PPARdelta regulates multiple proinflammatory pathways to suppress atherosclerosis.
1/2008	PPAR delta as a therapeutic target in metabolic disease.
1/2007	PPAR delta agonists and metabolic diseases.
2/2006	PPARdelta regulates glucose metabolism and insulin sensitivity.
10/2003	Transcriptional repression of atherogenic inflammation: modulation by PPARdelta.
4/2003	Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity.

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Chih-Hao Lee Research Topics

Disease

14	Inflammation (Inflammations) 01/2022 - 10/2003
14	Insulin Resistance 03/2020 - 06/2003
7	Obesity 03/2020 - 04/2003
7	Metabolic Diseases (Metabolic Disease) 07/2014 - 06/2003
7	Atherosclerosis 03/2008 - 10/2002
6	Type 2 Diabetes Mellitus (MODY) 04/2015 - 05/2004
5	Neoplasms (Cancer) 12/2020 - 01/2014
4	Cardiovascular Diseases (Cardiovascular Disease) 12/2021 - 02/2005
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 04/2015 - 01/2008
3	Hyperglycemia 01/2013 - 02/2006
2	Fatty Liver 03/2022 - 03/2020
2	Heart Failure 12/2021 - 01/2021
2	Overnutrition 05/2017 - 03/2012
2	Carcinoma (Carcinomatosis) 02/2015 - 08/2014
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2014 - 07/2013
2	Neuroinflammatory Diseases 01/2014 - 01/2014
2	Anemia 06/2013 - 04/2013
2	Hypertriglyceridemia 04/2013 - 01/2007
2	Coronary Artery Disease (Coronary Atherosclerosis) 02/2006 - 06/2003
1	Non-alcoholic Fatty Liver Disease 03/2022
1	Atrial Fibrillation 12/2021
1	Melanoma (Melanoma, Malignant) 12/2020
1	Amyloid Plaque 01/2020
1	Ischemia 01/2018
1	Hypoxia (Hypoxemia) 01/2018
1	Starvation 01/2018
1	Chronic Obstructive Pulmonary Disease (COPD) 01/2017
1	Alzheimer Disease (Alzheimer's Disease) 01/2016
1	Body Weight (Weight, Body) 12/2015
1	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2014
1	Ischemic Stroke 01/2014
1	Cerebral Hemorrhage 01/2014
1	Hypertension (High Blood Pressure) 01/2014
1	Fibrosis (Cirrhosis) 10/2013
1	Thalassemia 06/2013
1	Hemochromatosis (Bronze Diabetes) 06/2013
1	Iron Overload 06/2013

Drug/Important Bio-Agent (IBA)

11	Glucose (Dextrose)FDA LinkGeneric 03/2020 - 05/2004
8	LipidsIBA 01/2021 - 10/2003
8	PPAR deltaIBA 06/2008 - 04/2003
6	Fatty Acids (Saturated Fatty Acids)IBA 01/2017 - 06/2003
4	IronIBA 01/2020 - 04/2013
4	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 01/2012 - 05/2004
3	Interleukin-4 (Interleukin 4)IBA 10/2017 - 09/2011
3	AntioxidantsIBA 01/2014 - 12/2010
3	Insulin (Novolin)FDA Link 01/2013 - 05/2004
3	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 09/2012 - 06/2003
3	CytokinesIBA 01/2012 - 06/2008
2	Amyloid beta-PeptidesIBA 01/2020 - 01/2016
2	MetalsIBA 01/2020 - 06/2013
2	Proteins (Proteins, Gene)FDA Link 08/2019 - 02/2015
2	RibonucleoproteinsIBA 08/2019 - 02/2015
2	Messenger RNA (mRNA)IBA 08/2019 - 02/2015
2	CeramidesIBA 05/2017 - 03/2012
2	Biological ProductsIBA 01/2017 - 07/2014
2	Co-Repressor ProteinsIBA 07/2013 - 03/2008
2	Triglycerides (Triacylglycerol)IBA 04/2013 - 02/2003
2	Nonesterified Fatty Acids (NEFA)IBA 04/2012 - 01/2012
2	CholesterolIBA 03/2012 - 02/2005
2	AdipokinesIBA 01/2012 - 11/2008
2	PPAR alphaIBA 01/2007 - 05/2004
2	PPAR gammaIBA 01/2007 - 10/2002
2	LigandsIBA 02/2005 - 10/2003
1	Liver X ReceptorsIBA 03/2022
1	HMGB1 Protein (HMG1)IBA 03/2022
1	3-glucopyranosyloxybutanolideIBA 01/2022
1	Interleukin-12 (IL 12)IBA 01/2022
1	Interferon Type IIBA 01/2022
1	Tricarboxylic AcidsIBA 12/2021
1	Conditioned Culture MediaIBA 12/2020
1	methyl malonateIBA 12/2020
1	LipopolysaccharidesIBA 12/2020
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2018
1	Oxygen (Dioxygen)IBA 01/2018
1	Amino Acids FDA Link 01/2018
1	Transcription Factors (Transcription Factor)IBA 01/2018
1	Sulfur Amino AcidsIBA 01/2018
1	SmokeIBA 01/2017
1	LeptinIBA 12/2015
1	tylophorineIBA 02/2015
1	Mechanistic Target of Rapamycin Complex 1IBA 08/2014
1	Small Interfering RNA (siRNA)IBA 08/2014
1	IsoenzymesIBA 08/2014
1	Glutamic Acid (Glutamate)FDA Link 08/2014
1	Glutamine (L-Glutamine)FDA Link 08/2014
1	BenzoquinonesIBA 08/2014
1	GlutaminaseIBA 08/2014
1	LycopeneIBA 01/2014
1	Calcium Channel Blockers (Blockers, Calcium Channel)IBA 01/2014
1	Nicardipine (Dagan)FDA LinkGeneric 01/2014
1	Carotenoids (Carotene)IBA 01/2014
1	Ethanol (Ethyl Alcohol)IBA 10/2013
1	Carbon Tetrachloride (Tetrachloromethane)IBA 10/2013
1	Thyroid Hormone Receptors (Thyroid Hormone Receptor)IBA 07/2013
1	RetinoidsIBA 07/2013
1	Lipoprotein Lipase (Diacylglycerol Lipase)IBA 04/2013
1	Interleukin-13IBA 01/2013

Therapy/Procedure

4	Therapeutics 01/2014 - 03/2008
2	Mediterranean Diet 05/2017 - 04/2015
1	Glycemic Control 01/2013